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Lead poisoning in children

Introduction

Who’s more at risk from the IQ effects: your baby or your grade-schooler?

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08/05/2008
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Lead: is your child at risk?

Contrary to what you might imagine from last year’s headlines about toxic toys, older children are more vulnerable to the harmful effects of lead exposure according to a Cincinnati Children's Hospital Medical Center study.


“Although we typically worry about protecting toddlers from lead exposure, our study shows that parents and pediatricians should be just as, if not more concerned about lead exposure in school-aged children,” says Dr Richard Hornung, a researcher in the division of general and community pediatrics at Cincinnati Children’s and the study’s main author.

The researchers found that blood lead concentrations (BPb) at age 6, compared to those at younger ages, are more strongly associated with IQ and reduced gray matter in the area of the brain that’s involved in planning, complex thinking and moderating behavior. Although peak levels were generally seen in toddlers and tended to decline by age 6, those children whose lead levels didn’t fall had substantially greater decrements in intellectual ability than those more heavily exposed at age 2.

“Lead toxicity is difficult to recognize in a clinical setting, but it can have devastating effects,” says Bruce Lanphear, MD, director of the Cincinnati Children’s Environmental Health Center and the study’s senior author. “We found that children may be particularly vulnerable to lead exposure just as the child approaches school age, during a period of rapid cognitive development.”

Because IQ tests were not administered to children older than 6, it is unknown whether older children are even more vulnerable to environmental lead exposure, according to Dr Hornung.
Approximately 310,000 US children age 1 to 5 years have blood lead levels greater than 10 micrograms per deciliter, the level at which the Centers for Disease Control (CDC) recommends public health actions be initiated. But research has consistently shown that blood lead levels considerably lower than 10 micrograms per deciliter are associated with adverse effects.

Federal and state regulatory standards have helped to minimize or eliminate the amount of lead in US consumer products and occupational settings, according to the National Institute of Environmental Health Sciences (NIEHS). Today, the most common sources of lead exposure in the US are lead-based paint in older homes (be careful if you’re remodeling and you have young children), contaminated soil, household dust, drinking water, lead crystal and lead-glazed pottery.

While extreme lead exposure can cause a variety of neurological disorders, such as lack of muscular coordination, convulsions and coma, lower lead levels have been associated with measurable deficits in children’s mental development and behavioral problems. These include hyperactivity, or ADHD, lowered performance on intelligence tests, and deficits in fine motor function, hand-eye coordination and reaction time.


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